User blog comment:BigFanofEntertainment/Do you think Ronnie Anne will get her own spin-off show?/@comment-26901681-20170606063559/@comment-26302585-20170606173614

Here's the difference though. American Dad isn't a spin-off. It may look similar to Family Guy animation wise, but that doesn't mean anything. It's entirely it's own show, with no connection to Family Guy.