Lisa Loud

Lisa Marie Loud is a main character in The Loud House.

Biography
Lisa is the second-youngest child in the Loud family, second youngest of the youngest siblings, and tenth oldest, at 4 years old. She is often seen working on complex experiments, equations, and formulas. Her most annoying habit is her weird studies.

Early life
Before the beginning of the series, Lisa graduated from college with a PhD despite her age. She is also a recipient of the Nobel Prize.

Personality
Though the second-youngest of the Louds, Lisa is a child prodigy, so she's the smartest kid in the bunch. Because of this she often tends to be egocentric and sarcastic with other people. She speaks with a lateral lisp and usually has a stoic frown, though she does smile from time to time. She is not as excited as her siblings, although sometimes she becomes in that state when something really good happen, like when she and the other sisters discover about Lincoln's romantic situation in "Heavy Meddle". Nonetheless she likes to be with her siblings and have fun with them even if she doesn't express it.

In many episodes, she can be seen working on strange experiments. In "Left in the Dark", she creates an Oreo shaped cookie called "Gloweos" with the infused DNA of a jellyfish and if someone eat it all his/her body will glow. One of her favorite hobbies are resolving very difficult math problems. She also likes to study the poop and bathroom habits of her siblings, something they all find gross and annoying.

As seen in "Overnight Success", Lisa not only likes to realize experiments with her siblings, but also she likes to realize them with people outside of her family.

Though easily the most mature of her siblings, Lisa is still a child not above childish plays like food fight. She has has her own mischievous side. For the most part her pranks are hidden in unassuming objects; such as acne cream, sunscreen, mouthwash, etc., with results like turning skin blue, mild sunburns, and hot-pepper induced fever, respectively. Lisa is also completely willing to join in the madness caused by her siblings, whether it be disputes over money, the "sweet spot", or just playing along.

Contrasting most of her family, Lisa is very honest and blunt about what is on her mind. Lisa's brutal honesty isn't so much out of a sense of morality, but because she doesn't want wasted brain space by making up a lie. This also makes her incapable of keeping a secret. Like Lincoln she's very individual in contrast to rest of the sisters as seen in "It's a Loud, Loud, Loud, Loud, House".

Nick Description
"Lisa Loud is smarter than the rest of her siblings combined. She spends most of her time in her lab setting off mysterious explosions, but she's always willing to help out with homework or explain the structural flaws in someone's pillow fort. She loves her test subjects siblings!"

Appearance
Lisa has short shaggy brown hair and wears large glasses to help her see. She wears a green turtleneck sweater, red pants and brown shoes, all of which droop down to illustrate her stoic demeanor.

Her sleepwear includes a lime green nightshirt with matching pants. Her swimwear consists of blue goggles and a green one-piece with a small purple line in the middle.

Her siblings generally
She considers her siblings less intelligent due to her great intelligence. Usually she uses them as test subjects for her experiments much to their annoyance. She doesn't seem to have much of a connection with anyone, but she really loves her family, and is always available to help them with any problem.

Lincoln
Lincoln doesn't have a lot of interactions with her, however he's afraid of her being angry because he ruined something.

In "Butterfly Effect", Lincoln breaks Lisa's chemical bottles with his yoyo and he fearfully believes Lisa will get mad for what he did, but instead of being angry she becomes ecstatic with him and thanks him for proving her hypothesis and for admitting what he did.

In "Heavy Meddle", she easily finds out about Lincoln's secret that he's being picked on at school. She states that she does not have enough room in her brain for keeping it to herself and tells it to Lynn, who in turn tells the other sisters, much to his chagrin. Though this is likely out of concern for the well-being of their only brother.

Lincoln is very disgusted when Lisa uses her family as lab rats and performs experiments on them without their knowledge. He angrily yelled at her when she experimented on Leni in "Project Loud House" and Lily in "Changing the Baby".

Lori
Lisa and Lori don't have a lot of interaction, although Lori already knows about Lisa's strange experiments. She hates Lisa's poop study as shown in "Undie Pressure", and doesn't like that she uses her siblings as "guinea pigs" as shown in "Left in the Dark". In "Driving Miss Hazy", Lisa does Lori's math homework in exchange for driving her to the planetarium.

Leni
The relationship that Lisa has with Leni is like Dexter and Dee Dee's relationship from Dexter's Laboratory. When Lisa creates a new invention, Leni is the first person whom she tests it on, and this could be because of Leni's poor intelligence. This is evidenced in various episodes like in "Project Loud House" when Lisa changed Leni's blemish cream for an experimental skin pigmentation ointment, turning her skin blue.

In "Butterfly Effect", Leni becomes smarter than Lisa after being hit in the head with a coat rack. This caused Lisa to give up on science, and gets a job on a gas station.

Given their complete opposite IQ levels, Leni's doltishness tends to get on Lisa's nerves at times.

Luna
Lisa and Luna don't have a lot of interaction between them. However in "The Sweet Spot", is revealed that Luna's singing annoys Lisa because it gives her tinnitus. Also in "For Bros About to Rock" is revealed that Luna ruins her first opera.

Luan
She and Lisa don't have too much interaction. Like all her siblings she gets annoyed by Luan's unfunny jokes. In "Left in the Dark", Lisa uses her to prove her "Gloweos" cookie, resulting in Luan's entire body glowing.

Lynn
She and Lisa don't have too much interaction. In "Butterfly Effect", it is revealed that Lisa tutors Lynn for her exams to let her stay in her sport teams. In "Heavy Meddle" Lisa told Lynn about Lincoln's problem with bully.

In "In Tents Debate", they both want to go to Dairyland for their family vacation and try to get Lincoln to vote for their side.

In "Heavy Meddle", when Lisa couldn't store Lincoln's secret that he was being picked on at school in her brain, she told Lynn who told everyone else and claimed Lynn's brain had plenty of room. Lynn thought it was a compliment at first, but then realized what her genius sister meant.

Lily
Lisa has a good friendship with her, as both of them have to share a room. In "Changing the Baby", Lisa tries to use Lily on an experiment that appears to be very dangerous. She also tries to implement her interests on Lily because she has no one else whom shares the same interests as her.

Trivia

 * Lisa is named after one of Chris Savino's five sisters.
 * Lisa's sweater was originally blue before being changed to green in development.
 * She is the first Loud sibling to have their middle name revealed, in April Fools Rules, where it's revealed her middle name is Marie.
 * This seems to allude Lisa Simpson from The Simpsons, as both Lisas have the same middle name.
 * As shown in "Sleuth or Consequences", Lisa doesn't use the bathroom because it steals time for her experiments and instead she uses Lily's training potty.
 * She prefers to sit in the back of the car in case the engine blows up or a low flying plane comes in.
 * It is shown in "Driving Miss Hazy" that she doesn't mind doing Lori's homework, but doesn't appreciate how it's not "challenging" enough.
 * In "For Bros About to Rock", it is revealed that Luna ruined her first opera by stage diving onto the orchestra.
 * In that same episode, Lisa was seen wearing fancy clothes for the first time in the series.
 * Lisa's ideal superpower is her brainpower, claiming she doesn't need one.
 * Her Polish name is Halszka, with the nickname "Hala".
 * It was revealed in "Chore and Peace" that Lisa pays the house's bills.
 * It is revealed in "Butterfly Effect" that Lisa tutors Lynn to let her stay on her sports teams.
 * It is confirmed in "Picture Perfect" that she is legally blind (thus she wears glasses).
 * She can be compared to fellow Nickelodeon character Jimmy Neutron, as well as Dexter from Cartoon Network's Dexter's Laboratory, Velma from the Scooby-Doo, and Walden from Nick Jr.'s Wow Wow Wubbzy!
 * Incidentally, Chris Savino has directed several episodes for Dexter's Laboratory.
 * She, along with Lynn, Luan, Lily, Lana, Lucy and Lincoln, are the only Loud kids who don't normally have their ears pierced.
 * Lisa is the fourth least feminine Loud sister after Lana, Luna, and Lynn.
 * She is the only Loud sister who's eyelashes aren't visible; not counting Lucy who's eyes have never been shown in the series.