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Carlos is the son of Hector and Rosa Casagrande, and the brother of Maria Santiago. He studied a lot and became a college professor of marine biology. He is married to Frida Puga, and he has four children with her: Carlota, CJ, Carl, and Carlitos. He is also Bobby and Ronnie Anne's maternal uncle.
PersonalityCarlos is a bibliophilic, absent-minded professor. He loves reading books so much, that he does this while doing other things at the same time. Reading books distracts him from what is happening around him, like he did not react to Lalo eating the food he is carrying, or on Carlino getting injured by a watermelon.
It was later shown in "Going Overboard" that Carlos had a secret interest of skateboarding and it was revealed that he was very good at it. He first got into it in college when he found out it was the most efficient method of getting around campus. It was also revealed that this is how he fell in love with Frida.
Since childhood he has sibling rivalry with Maria. Episodes "Cursed!" and "A Very Casagrandes Christmas" show that despite being an adult, he's still a momma's boy, because when he argues with Maria, he tattle tells on her to Rosa.
Carlos has short black hair, with some of the strands standing up, and also has thick, black eyebrows. He wears black glasses that have a square frame, a cream long sleeved shirt, a light green sweater, a red necktie, brown pants, a black belt with a yellow buckle, and dark brown shoes.